CRPS-Related Neurogenic Edema Responsive to Dextromethorphan/Quinidine

Myopathy in CRPS-I: disuse or neurogenic?

The diagnosis Complex Regional Pain Syndrome type I (CRPS-I) is based on clinical symptoms, including motor symptoms. Histological changes in muscle tissue may be present in the chronic phase of CRPS-I. Aim of this study was to analyze skeletal muscle tissue from amputated limbs of patients with CRPS-I, in order to gain more insight in factors that may play a role in changes in muscles in CRPS-...

Neurogenic pulmonary edema

Mechanisms of neurogenic pulmonary edema.

The pulmonary edema that develops quickly after a variety of cerebral insults, such as head injury, epileptic seizures, intracranial hypertension, and subarachnoid hemorrhage, is often accompanied by rapid flooding of airways with a protein-rich edema fluid (Weisman, 1939; MacKay, 1950; Richards, 1963; Simmons et al., 1968; Ciongoli and Posner, 1972; Theodore and Robin, 1976; Fisher and AboulNa...

Neuropeptides, neurogenic inflammation and complex regional pain syndrome (CRPS).

This review explains symptoms and nature of neuropeptide signaling and its importance for clinical symptoms of CRPS. Neurogenic inflammation regularly accompanies excitation of primary afferent nociceptors. It has two major components-plasma extravasation and vasodilatation. The most important mediators are the calcitonin gene-related peptide (CGRP) and substance P (SP). After peripheral trauma...

Neurogenic pulmonary edema: a current literature review.

Neurogenic pulmonary edema in the setting of critically ill neurologic patients is a condition that is not fully understood, and it is a relatively rare condition. Severe brain damage, such as cerebral and subarachnoid hemorrhage, head injuries and seizures, represents a risk factor for developing neurogenic pulmonary edema. Misdiagnosis and inappropriate management may worsen cerebral damage b...